Monday, April 18, 2011

How Drug Works: The Simple Explanation

How many of you when got a headache grabs an aspirin and used it? Aspirin has been used as a drug for headache for years. It works just like other drugs: binding itself with its receptor in cells and tissues. It’s a complex process, but can be explained in a simple way. So let’s see how it works!

Before going more further, let’s see about how our body interact with chemical compounds that enter or produce inside it. It works in same one mechanism: lock and key. The chemical compounds act as the “key” and our body as the “lock”. Every chemical compounds targeting a place in our body by this mechanism. There is a place in our cells or tissues that can respond to chemical compounds and act as a lock. It called binding site or receptor. Once a chemical compound binds with the right receptor, it will trigger one or more biological activities. The healing process occurs when the biological activities cure damages in tissues or kills pathogen in our body.

For drugs to trigger any biological activities, they need to bind together with the binding site. The process is controlled by the chemical property called stereoisomer. When the drug’s stereoisomer is math with the receptor’s stereoisomer, the drug will enter the cells or tissues and start the event. If the opposite happen, there will be no activity happen or the process will inhibit the real process that occurs if the same stereoisomer connected together.

That's how drug works in our body. It's better not to using drugs in a log period since it can make the receptor going blunt. If this happen, you'll need more dose and could make your liver damage. So keep health everyone!


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